Linked Life Data

15546721

Source:http://linkedlifedata.com/resource/pubmed/id/15546721

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
24
pubmed:dateCreated
2004-11-19
pubmed:abstractText
The synthesis of a series of Tocopherol long chain Fatty Alcohols (TFA) and their biological activities on the modulation of microglial activation are described. Specifically, the 2-(12-hydroxy-dodecyl)-2,5,7,8-tetramethyl-chroman-6-ol, the TFA bearing 12 carbon atoms on the side chain (n=12), shows the most potent inhibition of secretion on nitric oxide (NO) and tumour necrosis factor-alpha (TNF-alpha) by lipopolysaccharide (LPS)-activated microglia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0960-894X
pubmed:author
pubmed:issnType
Print
pubmed:day
20
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
6023-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Tocopherol long chain fatty alcohols decrease the production of TNF-alpha and NO radicals by activated microglial cells.
pubmed:affiliation
Laboratoire de chimie organique des substances naturelles, Centre de Neurochimie, UMR 7123 CNRS, Université Louis Pasteur, 67084 Strasbourg, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't