Source:http://linkedlifedata.com/resource/pubmed/id/15514000
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2005-3-24
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pubmed:abstractText |
The classification of samples using gene expression profiles is an important application in areas such as cancer research and environmental health studies. However, the classification is usually based on a small number of samples, and each sample is a long vector of thousands of gene expression levels. An important issue in parametric modeling for so many gene expression levels is the control of the number of nuisance parameters in the model. Large models often lead to intensive or even intractable computation, while small models may be inadequate for complex data.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1367-4803
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1055-61
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:15514000-Algorithms,
pubmed-meshheading:15514000-Bayes Theorem,
pubmed-meshheading:15514000-Cluster Analysis,
pubmed-meshheading:15514000-Gene Expression Profiling,
pubmed-meshheading:15514000-Gene Expression Regulation,
pubmed-meshheading:15514000-Humans,
pubmed-meshheading:15514000-Leukemia,
pubmed-meshheading:15514000-Models, Biological,
pubmed-meshheading:15514000-Models, Statistical,
pubmed-meshheading:15514000-Neoplasm Proteins,
pubmed-meshheading:15514000-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:15514000-Pattern Recognition, Automated,
pubmed-meshheading:15514000-Signal Transduction,
pubmed-meshheading:15514000-Tumor Markers, Biological
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pubmed:year |
2005
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pubmed:articleTitle |
A novel means of using gene clusters in a two-step empirical Bayes method for predicting classes of samples.
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pubmed:affiliation |
Department of Biostatistics and Applied Mathematics, The University of Texas M.D. Anderson Cancer Center Houston, TX 77030, USA. yuanji@mdanderson.org
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Evaluation Studies,
Research Support, N.I.H., Extramural
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