rdf:type |
|
lifeskim:mentions |
umls-concept:C0006142,
umls-concept:C0008976,
umls-concept:C0020710,
umls-concept:C0039286,
umls-concept:C0041618,
umls-concept:C0175672,
umls-concept:C0205195,
umls-concept:C0227843,
umls-concept:C0878174,
umls-concept:C1280519,
umls-concept:C1363878,
umls-concept:C1442488,
umls-concept:C1511726,
umls-concept:C1522673,
umls-concept:C1710684
|
pubmed:issue |
1
|
pubmed:dateCreated |
2004-12-16
|
pubmed:abstractText |
The 'Arimidex', Tamoxifen, Alone or in Combination (ATAC) trial is a randomized, double-blind trial comparing anastrozole ('Arimidex'), alone or in combination with tamoxifen, relative to tamoxifen alone as 5 year adjuvant treatment for post-menopausal women with early breast cancer. Since tamoxifen is associated with endometrial pathology, the ATAC endometrial sub-protocol was initiated to establish the background prevalence of intrauterine pathology, and to assess prospectively the incidence and nature of intrauterine changes following endocrine therapy. Another aim was to provide data from which advice could be generated on the best endometrium screening method for patients receiving tamoxifen.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0268-1161
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
20
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
294-301
|
pubmed:meshHeading |
pubmed-meshheading:15513977-Antineoplastic Agents, Hormonal,
pubmed-meshheading:15513977-Breast Neoplasms,
pubmed-meshheading:15513977-Chemotherapy, Adjuvant,
pubmed-meshheading:15513977-Clinical Protocols,
pubmed-meshheading:15513977-Double-Blind Method,
pubmed-meshheading:15513977-Endometrium,
pubmed-meshheading:15513977-Female,
pubmed-meshheading:15513977-Humans,
pubmed-meshheading:15513977-Hysteroscopy,
pubmed-meshheading:15513977-Nitriles,
pubmed-meshheading:15513977-Sensitivity and Specificity,
pubmed-meshheading:15513977-Tamoxifen,
pubmed-meshheading:15513977-Triazoles
|
pubmed:year |
2005
|
pubmed:articleTitle |
The ATAC ('Arimidex', Tamoxifen, Alone or in Combination) adjuvant breast cancer trial: baseline endometrial sub-protocol data on the effectiveness of transvaginal ultrasonography and diagnostic hysteroscopy.
|
pubmed:affiliation |
Department of Obstetrics and Gynaecology, St James' University Hospital, Leeds LS9 7TF, UK. Medsrd@stjames.leeds.ac.uk
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Multicenter Study
|