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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2004-10-14
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pubmed:abstractText |
The responses of plasma cortisol and adrenocorticotropic hormone (ACTH) were examined to intravenous injection of recombinant bovine tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (INF-gamma) in Holstein cows. INF-gamma induced dose-dependent rises in the plasma levels of both cortisol and ACTH, while TNF-alpha induced comparable plasma cortisol responses with much smaller rises in plasma ACTH. The results suggest a direct stimulatory action of TNF-alpha on cortisol secretion from the adrenal gland in cattle.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0047-1917
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
95-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15481863-Adrenal Cortex,
pubmed-meshheading:15481863-Adrenocorticotropic Hormone,
pubmed-meshheading:15481863-Animals,
pubmed-meshheading:15481863-Cattle,
pubmed-meshheading:15481863-Dose-Response Relationship, Drug,
pubmed-meshheading:15481863-Female,
pubmed-meshheading:15481863-Hydrocortisone,
pubmed-meshheading:15481863-Injections, Intravenous,
pubmed-meshheading:15481863-Interferon-gamma,
pubmed-meshheading:15481863-Random Allocation,
pubmed-meshheading:15481863-Recombinant Proteins,
pubmed-meshheading:15481863-Tumor Necrosis Factor-alpha
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pubmed:year |
2004
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pubmed:articleTitle |
Adrenocortical responses to tumor necrosis factor-alpha and interferon-gamma in cattle.
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pubmed:affiliation |
Laboratory of Biochemistry, Department of Biomedical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan. ahmed276@vetmed.hokudai.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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