Source:http://linkedlifedata.com/resource/pubmed/id/15457926
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2004-10-1
|
| pubmed:abstractText |
Different lactic acid bacteria have often been administered as a dietary means to enhance immune system activity. Based on this statement, the aim of the current work was to test the effects of a Lactobacillus casei DN114001 fermented milk consumption on the immune response capacity in middle-age volunteers. Forty-five healthy volunteers, 24 women and 21 men (aged: 51-58 years), were randomized into two groups to receive three cups per day of a L. casei DN114001 (10(8)-10(10) ufc/g) fermented milk (n = 23), or placebo (n = 22), during an 8-week period. Measurements were performed before (day 0), and after the nutritional intervention (day 56). After the trial, no changes in immune cell proportions were detected, but the probiotic-treated group increased oxidative burst capacity of monocytes (probiotic group: p = 0.029; placebo group: p = 0.625), as well as NK cells tumoricidal activity (probiotic group: p = 0.023; placebo group: p = 0.125). Results showed that daily intake of fermented milk containing Lactobacillus casei DN114001 could have a positive effect in modulating the innate immune defense in healthy-middle-age people.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
1138-7548
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
60
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
85-91
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| pubmed:dateRevised |
2008-11-21
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| pubmed:meshHeading |
pubmed-meshheading:15457926-Animals,
pubmed-meshheading:15457926-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:15457926-Diet,
pubmed-meshheading:15457926-Double-Blind Method,
pubmed-meshheading:15457926-Female,
pubmed-meshheading:15457926-Fermentation,
pubmed-meshheading:15457926-Flow Cytometry,
pubmed-meshheading:15457926-Humans,
pubmed-meshheading:15457926-Immunity, Innate,
pubmed-meshheading:15457926-K562 Cells,
pubmed-meshheading:15457926-Killer Cells, Natural,
pubmed-meshheading:15457926-Lactobacillus casei,
pubmed-meshheading:15457926-Male,
pubmed-meshheading:15457926-Middle Aged,
pubmed-meshheading:15457926-Milk,
pubmed-meshheading:15457926-Monocytes,
pubmed-meshheading:15457926-Placebos,
pubmed-meshheading:15457926-Probiotics,
pubmed-meshheading:15457926-Respiratory Burst,
pubmed-meshheading:15457926-Time Factors
|
| pubmed:year |
2004
|
| pubmed:articleTitle |
Daily ingestion of fermented milk containing Lactobacillus casei DN114001 improves innate-defense capacity in healthy middle-aged people.
|
| pubmed:affiliation |
Department of Physiology and Nutrition, University of Navarra, 31008 Pamplona, Spain.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|