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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2004-10-1
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pubmed:abstractText |
Idiopathic scoliosis (IS) affects approximately 1-2% of the population and has a heritable component. It is clear that in general IS displays the features of a complex genetic disorder; however families displaying a Mendelian inheritance pattern have been described. Our aim is to identify families segregating rare, highly penetrant loci. In the case described here the disorder appears to cosegregate with a chromosomal rearrangement.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
T
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0926-9630
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
86-9
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15457700-Adolescent,
pubmed-meshheading:15457700-Adult,
pubmed-meshheading:15457700-Child,
pubmed-meshheading:15457700-Child, Preschool,
pubmed-meshheading:15457700-Chromosome Breakage,
pubmed-meshheading:15457700-Chromosome Inversion,
pubmed-meshheading:15457700-Chromosome Mapping,
pubmed-meshheading:15457700-Chromosome Walking,
pubmed-meshheading:15457700-Chromosomes, Human, Pair 8,
pubmed-meshheading:15457700-Cloning, Molecular,
pubmed-meshheading:15457700-Female,
pubmed-meshheading:15457700-Gene Rearrangement,
pubmed-meshheading:15457700-Genetic Markers,
pubmed-meshheading:15457700-Humans,
pubmed-meshheading:15457700-In Situ Hybridization, Fluorescence,
pubmed-meshheading:15457700-Infant,
pubmed-meshheading:15457700-Male,
pubmed-meshheading:15457700-Pedigree,
pubmed-meshheading:15457700-Penetrance,
pubmed-meshheading:15457700-Scoliosis
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pubmed:year |
2002
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pubmed:articleTitle |
Positional cloning strategies for idiopathic scoliosis.
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pubmed:affiliation |
Department of Genetics, Washington University School of-Iedicine, St. Louis, AIO, USA.
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pubmed:publicationType |
Journal Article
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