Source:http://linkedlifedata.com/resource/pubmed/id/15346661
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2004-9-6
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pubmed:abstractText |
Our objective was to investigate the changes in maternal bone status in pregnancy. Amplitude-dependent speed of sound (AD-SoS) by quantitative ultrasound was measured in 100 healthy, White, pregnant women at term, and 100 White, healthy, non-pregnant and premenopausal women matched for age, as controls. In a subgroup of 50 women a longitudinal evaluation throughout pregnancy was performed. A significant reduction of AD-SoS was observed during pregnancy (controls: 2170 +/- 55 m/s; first trimester: 2118 +/- 46 m/s; second trimester: 2085 +/- 49 m/s; third trimester: 2081 +/- 51 m/s), showing a negative correlation with body mass index (r -0.31; p < 0.05) and a positive correlation with daily calcium intake (r 0.33; p < 0.05). Increased levels of urinary markers of bone resorption confirmed bone turnover (p < 0.05). Ultrasonographic study of bone is a simple, low-cost and safe method for measuring maternal bone mass in pregnancy. During pregnancy, there was a significant loss in AD-SoS that is an indicator of bone status; this decrease was higher in the second and third trimesters (p < 0.05), associated with a high bone turnover. It was more intense in women with a low calcium intake (p < 0.05).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amino Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium, Dietary,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxyproline,
http://linkedlifedata.com/resource/pubmed/chemical/deoxypyridinoline,
http://linkedlifedata.com/resource/pubmed/chemical/pyridinoline
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0951-3590
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
258-62
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:15346661-Adult,
pubmed-meshheading:15346661-Amino Acids,
pubmed-meshheading:15346661-Biological Markers,
pubmed-meshheading:15346661-Bone Density,
pubmed-meshheading:15346661-Bone Remodeling,
pubmed-meshheading:15346661-Bone and Bones,
pubmed-meshheading:15346661-Calcium, Dietary,
pubmed-meshheading:15346661-Cross-Sectional Studies,
pubmed-meshheading:15346661-Female,
pubmed-meshheading:15346661-Fingers,
pubmed-meshheading:15346661-Humans,
pubmed-meshheading:15346661-Hydroxyproline,
pubmed-meshheading:15346661-Longitudinal Studies,
pubmed-meshheading:15346661-Pregnancy
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pubmed:year |
2004
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pubmed:articleTitle |
Ultrasound measurement of pregnancy-induced changes in maternal bone mass: a longitudinal, cross-sectional and biochemical study.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Polytechnic University of Marche, Ancona, Italy.
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pubmed:publicationType |
Journal Article
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