Inflammation plays an important role in atherosclerosis. One of the most potent pro-inflammatory cytokines is tumor necrosis factor-alpha (TNF-alpha), a cytokine identified to have a pathogenic role in chronic inflammatory diseases such as rheumatoid arthritis (RA). The aim of the study was to evaluate the importance of TNF-alpha in atherogenesis.
Department of Medicine, University Hospital MAS, Experimental Cardiovascular Research, Wallenberg Laboratory, Ing 46, Plan 1, S-205 02 Malmö, Sweden. lena.branen@medforsk.mas.lu.se