Source:http://linkedlifedata.com/resource/pubmed/id/15337322
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2004-8-31
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pubmed:abstractText |
We performed mRNA in situ hybridization for TNF-alpha and IL-1beta from infant rats with group B streptococcal meningitis. Induction of both cytokines was seen in the ependyma and the meninges at 4 h. Both cytokines were expressed in the brain parenchyma at 12 h. Induction of IL-1beta mRNA was seen in vessels within the brain cortex. Neutrophilic infiltrate at all time points examined was minimal and could not account for the observed cytokine expression.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0169-328X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
128
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
95-102
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15337322-Animals,
pubmed-meshheading:15337322-Animals, Newborn,
pubmed-meshheading:15337322-Brain,
pubmed-meshheading:15337322-Gene Expression Regulation,
pubmed-meshheading:15337322-Humans,
pubmed-meshheading:15337322-In Situ Hybridization,
pubmed-meshheading:15337322-Interleukin-1,
pubmed-meshheading:15337322-Meningitis, Pneumococcal,
pubmed-meshheading:15337322-Rats,
pubmed-meshheading:15337322-Rats, Sprague-Dawley,
pubmed-meshheading:15337322-Streptococcal Infections,
pubmed-meshheading:15337322-Tumor Necrosis Factor-alpha
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pubmed:year |
2004
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pubmed:articleTitle |
Expression of proinflammatory cytokines tumor necrosis factor-alpha and interleukin-1beta in the brain during experimental group B streptococcal meningitis.
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pubmed:affiliation |
Division of Infectious Diseases, Drexel University College of Medicine, Philadelphia, PA, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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