Source:http://linkedlifedata.com/resource/pubmed/id/15313381
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2004-8-17
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pubmed:abstractText |
Serum response factor (SRF) is a transcription factor that plays an important role in cellular differentiation and cell cycle regulation. SRF function is regulated in part by alternative splicing. Little is known about the expression or role of these alternatively spliced isoforms during tumorigenesis. We hypothesized that there is a change in the splice variants during intestinal tumorigenesis and that this change promotes the tumor phenotype.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-4804
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
121
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
92-100
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15313381-Alternative Splicing,
pubmed-meshheading:15313381-Animals,
pubmed-meshheading:15313381-Apoptosis,
pubmed-meshheading:15313381-Cell Line, Tumor,
pubmed-meshheading:15313381-Cell Survival,
pubmed-meshheading:15313381-Cell Transformation, Neoplastic,
pubmed-meshheading:15313381-Colonic Neoplasms,
pubmed-meshheading:15313381-Humans,
pubmed-meshheading:15313381-Rats,
pubmed-meshheading:15313381-Serum Response Factor
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pubmed:year |
2004
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pubmed:articleTitle |
Serum response factor is alternatively spliced in human colon cancer.
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pubmed:affiliation |
Michael E. DeBakey Department of Surgery, Baylor College of Medicine, and The Houston Veterans Affairs Hospital, 2002 Holcombe Boulevard, Houston, TX 77030, USA. dhb@bcm.tmc.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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