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| pubmed-article:1530611 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:1530611 | pubmed:dateCreated | 1992-10-22 | lld:pubmed |
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| pubmed-article:1530611 | pubmed:abstractText | We report here the cDNA cloning of a putative gastrin receptor from enterochromaffin-like (ECL) carcinoid tumor of Mastomys natalensis. For this study, we used the polymerase chain reaction technique to amplify transmembrane domain sequences related to rat pancreatic cholecystokinin (CCK)-A receptor from the ECL tumor cDNA library. The amino acid sequence deduced from the cloned cDNA showed 85.7% and 49.0% identity to canine parietal cell gastrin receptor and rat pancreatic CCK-A receptor, respectively. Ligand binding studies using COS-7 cells transfected with the cDNA showed the same binding specificity for gastrin and CCK-8 as the gastrin receptor on the Mastomys carcinoid tumor membrane. Both gastrin and CCK-8 elevated free cytosolic calcium concentration in COS-7 cells expressing the cloned receptor. RNA blot analysis revealed the expression of the gastrin receptor in both Mastomys stomach and brain. | lld:pubmed |
| pubmed-article:1530611 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1530611 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1530611 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1530611 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1530611 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:1530611 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:1530611 | pubmed:author | pubmed-author:ItoMM | lld:pubmed |
| pubmed-article:1530611 | pubmed:author | pubmed-author:HosodaSS | lld:pubmed |
| pubmed-article:1530611 | pubmed:author | pubmed-author:ChiharaKK | lld:pubmed |
| pubmed-article:1530611 | pubmed:author | pubmed-author:NakataHH | lld:pubmed |
| pubmed-article:1530611 | pubmed:author | pubmed-author:TaniguchiTT | lld:pubmed |
| pubmed-article:1530611 | pubmed:author | pubmed-author:NakamuraAA | lld:pubmed |
| pubmed-article:1530611 | pubmed:author | pubmed-author:MatsuiTT | lld:pubmed |
| pubmed-article:1530611 | pubmed:author | pubmed-author:KinoshitaYY | lld:pubmed |
| pubmed-article:1530611 | pubmed:author | pubmed-author:ArimaNN | lld:pubmed |
| pubmed-article:1530611 | pubmed:author | pubmed-author:NaribayashiYY | lld:pubmed |
| pubmed-article:1530611 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1530611 | pubmed:day | 16 | lld:pubmed |
| pubmed-article:1530611 | pubmed:volume | 187 | lld:pubmed |
| pubmed-article:1530611 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1530611 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:1530611 | pubmed:pagination | 1151-7 | lld:pubmed |
| pubmed-article:1530611 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:1530611 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1530611 | pubmed:articleTitle | Cloning and characterization of gastrin receptor from ECL carcinoid tumor of Mastomys natalensis. | lld:pubmed |
| pubmed-article:1530611 | pubmed:affiliation | Department of Medicine, Kobe University School of Medicine, Japan. | lld:pubmed |
| pubmed-article:1530611 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1530611 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:1530611 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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