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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-8-12
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pubmed:abstractText |
We made a transgenic mouse that expresses Cre recombinase activity in inner ear hair cells by using a modified bacterial artificial chromosome containing Prestin. Cre recombinase activity was restricted to inner and outer hair cells, a subset of vestibular hair cells, spiral and vestibular ganglia in the inner ear, and a subset of cells in the testis, epididymis, and ear bone. This mouse will be useful for hair-cell-specific gene targeting.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1058-8388
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
231
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
199-203
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15305300-Animals,
pubmed-meshheading:15305300-Chromosomes, Artificial, Bacterial,
pubmed-meshheading:15305300-Epididymis,
pubmed-meshheading:15305300-Gene Targeting,
pubmed-meshheading:15305300-Hair Cells, Auditory, Inner,
pubmed-meshheading:15305300-Hair Cells, Auditory, Outer,
pubmed-meshheading:15305300-Integrases,
pubmed-meshheading:15305300-Male,
pubmed-meshheading:15305300-Mice,
pubmed-meshheading:15305300-Mice, Transgenic,
pubmed-meshheading:15305300-Molecular Motor Proteins,
pubmed-meshheading:15305300-Proteins,
pubmed-meshheading:15305300-Testis,
pubmed-meshheading:15305300-Vestibular Nerve,
pubmed-meshheading:15305300-Viral Proteins
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pubmed:year |
2004
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pubmed:articleTitle |
Creation of a transgenic mouse for hair-cell gene targeting by using a modified bacterial artificial chromosome containing Prestin.
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pubmed:affiliation |
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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