Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2004-8-3
pubmed:abstractText
The PEARLS study prospectively monitored selected nosocomial pathogens from 38 centres in 13 European, three Middle Eastern countries and South Africa during 2001-2002. Extended spectrum beta-lactamase (ESBL) production rates among Escherichia coli, Klebsiella pneumoniae, and Enterobacter spp. were 5.4% (142/2609), 18.2% (401/2,206) and 8.8% (204/2,328), respectively, for all study sites. The overall ESBL production rate for the combined Enterobacteriaceae was 10.5% (747/7,143), highest in Egypt, 38.5%, and Greece, 27.4%, and lowest in The Netherlands, 2.0%, and Germany, 2.6%. IEF, PCR and DNA sequencing determined 10.7% false positives among Enterobacter spp. when using NCCLS guidelines to screen for ESBL production. The prevalence of nosocomial methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium was 32.4% (294/908) and 8.7% (83/949), respectively. PEARLS provides baseline data against which prospective changes in resistant determinants and outcomes can be measured in this ongoing study.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0924-8579
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
119-24
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:15288309-Anti-Bacterial Agents, pubmed-meshheading:15288309-Cross Infection, pubmed-meshheading:15288309-Enterobacteriaceae, pubmed-meshheading:15288309-Enterobacteriaceae Infections, pubmed-meshheading:15288309-Enterococcus faecium, pubmed-meshheading:15288309-Europe, pubmed-meshheading:15288309-Gram-Positive Bacterial Infections, pubmed-meshheading:15288309-Humans, pubmed-meshheading:15288309-Incidence, pubmed-meshheading:15288309-Methicillin Resistance, pubmed-meshheading:15288309-Microbial Sensitivity Tests, pubmed-meshheading:15288309-Middle East, pubmed-meshheading:15288309-Population Surveillance, pubmed-meshheading:15288309-South Africa, pubmed-meshheading:15288309-Staphylococcus aureus, pubmed-meshheading:15288309-Vancomycin Resistance, pubmed-meshheading:15288309-beta-Lactamases
pubmed:year
2004
pubmed:articleTitle
Determining incidence of extended spectrum beta-lactamase producing Enterobacteriaceae, vancomycin-resistant Enterococcus faecium and methicillin-resistant Staphylococcus aureus in 38 centres from 17 countries: the PEARLS study 2001-2002.
pubmed:affiliation
Laboratories International for Microbiology Studies, 2122 Palmer Road, Schaumburg, IL 60173-3817, USA. sambouchillon@comcast.net
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't