Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
13
pubmed:dateCreated
2004-7-8
pubmed:abstractText
Cyclooxygenase-2 (Cox-2), an enzyme that catalyzes the synthesis of prostaglandins, is overexpressed in a variety of premalignant and malignant conditions, including urinary bladder cancer. In the present study, we examined the feasibility of using Cox-2 promoter-based replication-selective adenovirus for targeting bladder cancer cells that express Cox-2 transcriptional activity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1078-0432
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4342-8
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:15240520-Adenoviridae, pubmed-meshheading:15240520-Adenovirus E1A Proteins, pubmed-meshheading:15240520-Animals, pubmed-meshheading:15240520-Cell Line, Tumor, pubmed-meshheading:15240520-Cyclooxygenase 2, pubmed-meshheading:15240520-DNA, pubmed-meshheading:15240520-Gene Therapy, pubmed-meshheading:15240520-Humans, pubmed-meshheading:15240520-Isoenzymes, pubmed-meshheading:15240520-Luciferases, pubmed-meshheading:15240520-Membrane Proteins, pubmed-meshheading:15240520-Mice, pubmed-meshheading:15240520-Mice, Inbred BALB C, pubmed-meshheading:15240520-Models, Genetic, pubmed-meshheading:15240520-Neoplasm Transplantation, pubmed-meshheading:15240520-Plasmids, pubmed-meshheading:15240520-Promoter Regions, Genetic, pubmed-meshheading:15240520-Prostaglandin-Endoperoxide Synthases, pubmed-meshheading:15240520-RNA, Messenger, pubmed-meshheading:15240520-Recombination, Genetic, pubmed-meshheading:15240520-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:15240520-Sensitivity and Specificity, pubmed-meshheading:15240520-Time Factors, pubmed-meshheading:15240520-Transcription, Genetic, pubmed-meshheading:15240520-Transfection, pubmed-meshheading:15240520-Urinary Bladder Neoplasms
pubmed:year
2004
pubmed:articleTitle
A cox-2 promoter-based replication-selective adenoviral vector to target the cox-2-expressing human bladder cancer cells.
pubmed:affiliation
Division of Urology, Department of Organs Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
pubmed:publicationType
Journal Article