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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1992-10-15
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pubmed:abstractText |
Twenty-three yellow fever (YF) vaccine viruses and three wild-type YF viruses were propagated independently in human adenocarcinoma (SW13) cells and mosquito Aedes albopictus C6-36 cells. The three YF 17DD vaccine viruses were found to be slightly temperature sensitive (ts) at 39.5 degrees C versus 37.0 degrees C (efficiency of plaquing 0.04 to 0.1) following propagation in C6-36 but not in SW13 cells. A plaque-purified preparation of the 17DD vaccine manufactured in Brazil was ts when grown in C6-36 cells and remained ts when passaged back into the SW13 cell line.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0264-410X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
10
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
652-4
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:1523874-Aedes,
pubmed-meshheading:1523874-Animals,
pubmed-meshheading:1523874-Cell Line,
pubmed-meshheading:1523874-Hot Temperature,
pubmed-meshheading:1523874-Humans,
pubmed-meshheading:1523874-Phenotype,
pubmed-meshheading:1523874-Tumor Cells, Cultured,
pubmed-meshheading:1523874-Viral Vaccines,
pubmed-meshheading:1523874-Yellow fever virus
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pubmed:year |
1992
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pubmed:articleTitle |
Yellow fever 17DD vaccine virus is temperature sensitive when grown in mosquito C6-36 cells.
|
pubmed:affiliation |
Molecular Microbiology Group, School of Biological Sciences, University of Surrey, Guildford, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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