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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-6-29
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pubmed:abstractText |
The validity of molecular studies using RNA extracted from decades-old formalin-fixed and embedded tissue blocks is well documented. Formalin-fixed samples are, however, known to be poor materials for molecular biological applications. The aim of this study was to investigate the effect of formalin as a preservation agent on RNA quality and relevant molecular applications.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0036-5513
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
229-35
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pubmed:meshHeading |
pubmed-meshheading:15222633-Animals,
pubmed-meshheading:15222633-Electrophoresis, Agar Gel,
pubmed-meshheading:15222633-Formaldehyde,
pubmed-meshheading:15222633-Guanidines,
pubmed-meshheading:15222633-Liver,
pubmed-meshheading:15222633-Male,
pubmed-meshheading:15222633-Phenols,
pubmed-meshheading:15222633-RNA, Messenger,
pubmed-meshheading:15222633-Rats,
pubmed-meshheading:15222633-Rats, Wistar,
pubmed-meshheading:15222633-Ribonuclease, Pancreatic,
pubmed-meshheading:15222633-Spectrophotometry, Ultraviolet,
pubmed-meshheading:15222633-Tissue Fixation
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pubmed:year |
2004
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pubmed:articleTitle |
Effect of formalin on extraction of mRNA from a formalin-fixed sample: a basic investigation.
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pubmed:affiliation |
Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
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pubmed:publicationType |
Journal Article
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