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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-6-24
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pubmed:abstractText |
Granulocyte colony-stimulating factor (G-CSF) is often administered to patients with chemotherapy-induced leukocytopenia. However, adequate attention has not been paid to its effects on cancer immunology. Reported by us and others, G-CSF often induces immunosuppression and down-regulation of response T helper (Th)2 directed immune reaction both in vivo and in vitro. In this study, we analyzed the effects of G-CSF on interferon (IFN)-gamma production and autologous tumor killing (ATK) activities of peripheral blood mononuclear cells (PBMCs).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1046-7408
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pubmed:author |
pubmed-author:ChishimaFumihisaF,
pubmed-author:HattaYoshihiroY,
pubmed-author:HayakawaSatoshiS,
pubmed-author:HorieTakashiT,
pubmed-author:Karasaki-SuzukiMikiM,
pubmed-author:KomineShihokoS,
pubmed-author:NemotoNorimichiN,
pubmed-author:OhtaYoshiakiY,
pubmed-author:SeoNaohiroN,
pubmed-author:SheikhAleemuzzamanA,
pubmed-author:SugitaKenjiK,
pubmed-author:YamamotoTatsuoT
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pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
81-7
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15214947-Cytotoxicity, Immunologic,
pubmed-meshheading:15214947-Female,
pubmed-meshheading:15214947-Granulocyte Colony-Stimulating Factor,
pubmed-meshheading:15214947-Humans,
pubmed-meshheading:15214947-Interferon-gamma,
pubmed-meshheading:15214947-Interleukin-12,
pubmed-meshheading:15214947-Interleukin-2,
pubmed-meshheading:15214947-Lymphocytes,
pubmed-meshheading:15214947-Ovarian Neoplasms,
pubmed-meshheading:15214947-RNA, Messenger,
pubmed-meshheading:15214947-Receptors, Granulocyte Colony-Stimulating Factor,
pubmed-meshheading:15214947-Tumor Cells, Cultured
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pubmed:year |
2004
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pubmed:articleTitle |
Granulocyte colony-stimulating factor suppresses autologous tumor killing activity of the peripheral blood lymphocytes in the patients with ovarian carcinoma.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Nihon University School of Medicine, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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