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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-6-23
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pubmed:abstractText |
Esophagectomy for esophageal cancer is associated with substantial postoperative morbidity as a result of infectious complications. In a prior phase II study, granulocyte colony-stimulating factor (G-CSF) was shown to improve leukocyte function and to reduce infection rates after esophagectomy. The aim of the current randomized, placebo-controlled, multicenter phase III trial was to investigate the clinical efficacy of perioperative G-CSF administration in reducing infection and mortality after esophagectomy for esophageal cancer.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-10075357,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-10803937,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-10950800,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-11098963,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-11171733,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-11257020,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-11301408,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-11565672,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-11904116,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-12519588,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-1331619,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-1596128,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-3395815,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-3594139,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-6824878,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-7165009,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-7482272,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-7786985,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-8582499,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-8833041,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-8980882,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-9230656,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-9310604,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-9559614,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-9641012,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15213620-9806037
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0003-4932
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pubmed:author |
pubmed-author:EngertAndreasA,
pubmed-author:GrassGuidoG,
pubmed-author:HoelscherArnulf HAH,
pubmed-author:HubelKaiK,
pubmed-author:KnoefelWolfram TWT,
pubmed-author:LippertHansH,
pubmed-author:LoehleinDietrichD,
pubmed-author:MansmannGeorgG,
pubmed-author:SchaeferHartmutH,
pubmed-author:UlrichBernward CBC,
pubmed-author:WassmerGernotG
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pubmed:issnType |
Print
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pubmed:volume |
240
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
68-75
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15213620-Adult,
pubmed-meshheading:15213620-Aged,
pubmed-meshheading:15213620-Anti-Infective Agents,
pubmed-meshheading:15213620-Double-Blind Method,
pubmed-meshheading:15213620-Esophageal Neoplasms,
pubmed-meshheading:15213620-Esophagectomy,
pubmed-meshheading:15213620-Female,
pubmed-meshheading:15213620-Granulocyte Colony-Stimulating Factor,
pubmed-meshheading:15213620-Humans,
pubmed-meshheading:15213620-Infection,
pubmed-meshheading:15213620-Male,
pubmed-meshheading:15213620-Mediastinitis,
pubmed-meshheading:15213620-Middle Aged,
pubmed-meshheading:15213620-Perioperative Care,
pubmed-meshheading:15213620-Pneumonia,
pubmed-meshheading:15213620-Postoperative Complications,
pubmed-meshheading:15213620-Premedication,
pubmed-meshheading:15213620-Recombinant Proteins,
pubmed-meshheading:15213620-Risk Factors,
pubmed-meshheading:15213620-Sepsis,
pubmed-meshheading:15213620-Surgical Wound Infection,
pubmed-meshheading:15213620-Urinary Tract Infections
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pubmed:year |
2004
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pubmed:articleTitle |
Perioperative granulocyte colony-stimulating factor does not prevent severe infections in patients undergoing esophagectomy for esophageal cancer: a randomized placebo-controlled clinical trial.
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pubmed:affiliation |
Department of Visceral and Vascular Surgery, University of Cologne, Germany.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase III
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