Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2004-6-11
pubmed:abstractText
We are investigating the utility of a new ultrasonic tissue characterization technique, specifically two-dimensional (2-D) spectrum analysis of radio-frequency backscatter signals, which promises to provide quantitative measures of the physical properties of tissue microstructures. Previously successful 1-D spectrum analysis is expanded to 2-D to more fully characterize diagnostically significant features of biological tissue. Two new spectral functions, radially integrated spectral power (RISP) and angularly integrated spectral power (AISP), are defined to quantitatively characterize tissue properties. This new approach is applied to the diagnosis of in vivo ocular melanomas. Our initial results indicate that 2-D spectrum analysis can provide significant new information on tissue anisotropy that are not apparent in 1-D spectra. Acoustic scattering models are applied to relate the 2-D spectral parameters to the physical properties (e.g., size and shape) of biological tissues.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0094-2405
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1032-9
pubmed:dateRevised
2011-5-5
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Ultrasonic tissue characterization using 2-D spectrum analysis and its application in ocular tumor diagnosis.
pubmed:affiliation
Department of Radiation Oncology, Columbia University, New York, New York 10032, USA. tl58@columbia.edu
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Evaluation Studies