15161854

Source:http://linkedlifedata.com/resource/pubmed/id/15161854

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017262, umls-concept:C0031621, umls-concept:C0079633, umls-concept:C0086418, umls-concept:C0185117, umls-concept:C0443199, umls-concept:C1314939, umls-concept:C1337092, umls-concept:C1419621, umls-concept:C1522558, umls-concept:C1705079, umls-concept:C2911684
pubmed:issue	6
pubmed:dateCreated	2004-5-26
pubmed:abstractText	To investigate the role of the phosphatidylinositol 3-kinase (PI3K) pathway and the signal mediator AP-1 in monocyte chemotactic protein (MCP)-1 and interleukin (IL)-8 gene expression in human retinal pigment epithelial (hRPE) cells.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/EY07003, http://linkedlifedata.com/resource/pubmed/grant/EY09441
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7703701
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/AKT1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-8, http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylinositol 3-Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Protein-Serine-Threonine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factor AP-1, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	0146-0404
pubmed:author	pubmed-author:BianZong-MeiZM, pubmed-author:ElnerSusan GSG, pubmed-author:ElnerVictor MVM, pubmed-author:YoshidaAyakoA
pubmed:issnType	Print
pubmed:volume	45
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1887-96
pubmed:dateRevised	2010-11-18
pubmed:meshHeading	pubmed-meshheading:15161854-Blotting, Western, pubmed-meshheading:15161854-Cells, Cultured, pubmed-meshheading:15161854-Chemokine CCL2, pubmed-meshheading:15161854-Coculture Techniques, pubmed-meshheading:15161854-Dose-Response Relationship, Drug, pubmed-meshheading:15161854-Enzyme Inhibitors, pubmed-meshheading:15161854-Enzyme-Linked Immunosorbent Assay, pubmed-meshheading:15161854-Gene Expression Regulation, pubmed-meshheading:15161854-Humans, pubmed-meshheading:15161854-Interleukin-1, pubmed-meshheading:15161854-Interleukin-8, pubmed-meshheading:15161854-Monocytes, pubmed-meshheading:15161854-Phosphatidylinositol 3-Kinases, pubmed-meshheading:15161854-Phosphorylation, pubmed-meshheading:15161854-Pigment Epithelium of Eye, pubmed-meshheading:15161854-Protein-Serine-Threonine Kinases, pubmed-meshheading:15161854-Proto-Oncogene Proteins, pubmed-meshheading:15161854-Proto-Oncogene Proteins c-akt, pubmed-meshheading:15161854-RNA, Messenger, pubmed-meshheading:15161854-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:15161854-Signal Transduction, pubmed-meshheading:15161854-Time Factors, pubmed-meshheading:15161854-Transcription Factor AP-1, pubmed-meshheading:15161854-Tumor Necrosis Factor-alpha
pubmed:year	2004
pubmed:articleTitle	Differential involvement of phosphoinositide 3-kinase/Akt in human RPE MCP-1 and IL-8 expression.
pubmed:affiliation	Department of Ophthalmology, University of Michigan, Ann Arbor 48105, USA.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't