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15146414
Source:
http://linkedlifedata.com/resource/pubmed/id/15146414
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Statements in which the resource exists as a subject.
Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0003873
,
umls-concept:C0016030
,
umls-concept:C0033268
,
umls-concept:C0080125
,
umls-concept:C0127082
,
umls-concept:C0392756
,
umls-concept:C1550315
pubmed:issue
5
pubmed:dateCreated
2004-5-17
pubmed:abstractText
To investigate whether retroviral gene transfer of ribozymes targeting matrix metalloproteinase 1 (MMP-1) inhibits the production of MMP-1 in rheumatoid arthritis synovial fibroblasts (RASFs) and reduces the invasiveness of these cells in vivo.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/0370605
pubmed:citationSubset
AIM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Collagenases
,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 1
,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 13
,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 9
,
http://linkedlifedata.com/resource/pubmed/chemical/Mmp13 protein, mouse
,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Catalytic
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0004-3591
pubmed:author
pubmed-author:AicherWilhelm KWK
,
pubmed-author:AlexanderDorotheaD
,
pubmed-author:GayRenate ERE
,
pubmed-author:GaySteffenS
,
pubmed-author:Müller-LadnerUlfU
,
pubmed-author:MawrinChristianC
,
pubmed-author:MichelBeat ABA
,
pubmed-author:PapThomasT
,
pubmed-author:RutkauskaiteEditaE
,
pubmed-author:SchedelJörgJ
,
pubmed-author:SeemayerChristian ACA
,
pubmed-author:ZachariasWolfgangW
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1448-56
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:15146414-Animals
,
pubmed-meshheading:15146414-Arthritis, Rheumatoid
,
pubmed-meshheading:15146414-Cartilage
,
pubmed-meshheading:15146414-Cells, Cultured
,
pubmed-meshheading:15146414-Collagenases
,
pubmed-meshheading:15146414-Female
,
pubmed-meshheading:15146414-Fibroblasts
,
pubmed-meshheading:15146414-Gene Therapy
,
pubmed-meshheading:15146414-Matrix Metalloproteinase 1
,
pubmed-meshheading:15146414-Matrix Metalloproteinase 13
,
pubmed-meshheading:15146414-Matrix Metalloproteinase 9
,
pubmed-meshheading:15146414-Mice
,
pubmed-meshheading:15146414-Mice, SCID
,
pubmed-meshheading:15146414-Nucleic Acid Conformation
,
pubmed-meshheading:15146414-RNA, Catalytic
,
pubmed-meshheading:15146414-Retroviridae
,
pubmed-meshheading:15146414-Synovial Membrane
pubmed:year
2004
pubmed:articleTitle
Ribozymes that inhibit the production of matrix metalloproteinase 1 reduce the invasiveness of rheumatoid arthritis synovial fibroblasts.
pubmed:affiliation
Otto-von-Guericke-University, University Hospital Magdeburg, Leipziger-Strasse 44, D-39120 Magdeburg, Germany.
pubmed:publicationType
Journal Article