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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2004-4-15
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pubmed:abstractText |
Mesoderm migration in the Drosophila gastrula depends on the fibroblast growth factor (FGF) receptor Heartless (Htl). During gastrulation Htl is required for adhesive interactions of the mesoderm with the ectoderm and for the generation of protrusive activity of the mesoderm cells during migration. After gastrulation Htl is essential for the differentiation of dorsal mesodermal derivatives. It is not known how Htl is activated, because its ligand has not yet been identified.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0960-9822
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
20
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
659-67
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15084280-Amino Acid Sequence,
pubmed-meshheading:15084280-Animals,
pubmed-meshheading:15084280-Blotting, Northern,
pubmed-meshheading:15084280-Cell Size,
pubmed-meshheading:15084280-Chromosome Mapping,
pubmed-meshheading:15084280-DNA, Complementary,
pubmed-meshheading:15084280-Drosophila,
pubmed-meshheading:15084280-Drosophila Proteins,
pubmed-meshheading:15084280-Gastrula,
pubmed-meshheading:15084280-Gene Expression Profiling,
pubmed-meshheading:15084280-Immunohistochemistry,
pubmed-meshheading:15084280-In Situ Hybridization,
pubmed-meshheading:15084280-Ligands,
pubmed-meshheading:15084280-Mesoderm,
pubmed-meshheading:15084280-Molecular Sequence Data,
pubmed-meshheading:15084280-Protein-Tyrosine Kinases,
pubmed-meshheading:15084280-RNA Interference,
pubmed-meshheading:15084280-Receptors, Fibroblast Growth Factor,
pubmed-meshheading:15084280-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:15084280-Sequence Alignment,
pubmed-meshheading:15084280-Sequence Analysis, DNA,
pubmed-meshheading:15084280-Signal Transduction
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pubmed:year |
2004
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pubmed:articleTitle |
FGF8-like1 and FGF8-like2 encode putative ligands of the FGF receptor Htl and are required for mesoderm migration in the Drosophila gastrula.
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pubmed:affiliation |
Institut für Genetik, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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