rdf:type |
|
lifeskim:mentions |
umls-concept:C0007600,
umls-concept:C0014597,
umls-concept:C0017152,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0038633,
umls-concept:C0061231,
umls-concept:C0079488,
umls-concept:C0079633,
umls-concept:C0086418,
umls-concept:C0227813,
umls-concept:C1704242
|
pubmed:issue |
2
|
pubmed:dateCreated |
2004-4-7
|
pubmed:abstractText |
The role of teprenone in Helicobacter pylori-associated gastritis has yet to be determined. To investigate the effect of teprenone on inflammatory cell infiltration, and on H. pylori colonization of the gastric mucosa in H. pylori-infected patients, we first compared the effect of teprenone with that of both histamine H2 receptor antagonists (H2-RA) and sucralfate on the histological scores of H. pylori gastritis. We then examined its in vitro effect on H. pylori-induced interleukin (IL)-8 production in MKN28 gastric epithelial cells.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1083-4389
|
pubmed:author |
pubmed-author:FutagamiSeijiS,
pubmed-author:GudisKatyaK,
pubmed-author:HiratsukaTetsuroT,
pubmed-author:IwakiriKatsuhikoK,
pubmed-author:MiyakeKazumasaK,
pubmed-author:NishigakiHitoshiH,
pubmed-author:SakamotoChoitsuC,
pubmed-author:ShinjiYokoY,
pubmed-author:ShinokiKeiK,
pubmed-author:TsukuiTakuT,
pubmed-author:WadaKenK,
pubmed-author:YamadaNobutakaN
|
pubmed:issnType |
Print
|
pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
130-7
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15068414-Anti-Ulcer Agents,
pubmed-meshheading:15068414-Biopsy,
pubmed-meshheading:15068414-Cell Line,
pubmed-meshheading:15068414-Diterpenes,
pubmed-meshheading:15068414-Epithelial Cells,
pubmed-meshheading:15068414-Female,
pubmed-meshheading:15068414-Gastric Mucosa,
pubmed-meshheading:15068414-Gastritis,
pubmed-meshheading:15068414-Helicobacter Infections,
pubmed-meshheading:15068414-Helicobacter pylori,
pubmed-meshheading:15068414-Histamine H2 Antagonists,
pubmed-meshheading:15068414-Humans,
pubmed-meshheading:15068414-Interleukin-8,
pubmed-meshheading:15068414-Male,
pubmed-meshheading:15068414-Middle Aged,
pubmed-meshheading:15068414-Neutrophil Infiltration,
pubmed-meshheading:15068414-Nizatidine,
pubmed-meshheading:15068414-Pepsinogen A,
pubmed-meshheading:15068414-Pepsinogen C,
pubmed-meshheading:15068414-Sucralfate,
pubmed-meshheading:15068414-Urease
|
pubmed:year |
2004
|
pubmed:articleTitle |
Teprenone, but not H2-receptor blocker or sucralfate, suppresses corpus Helicobacter pylori colonization and gastritis in humans: teprenone inhibition of H. pylori-induced interleukin-8 in MKN28 gastric epithelial cell lines.
|
pubmed:affiliation |
Third Department of Internal Medicine, Department of Pathology, Tokyo, Japan.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|