Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2004-4-7
pubmed:abstractText
The role of teprenone in Helicobacter pylori-associated gastritis has yet to be determined. To investigate the effect of teprenone on inflammatory cell infiltration, and on H. pylori colonization of the gastric mucosa in H. pylori-infected patients, we first compared the effect of teprenone with that of both histamine H2 receptor antagonists (H2-RA) and sucralfate on the histological scores of H. pylori gastritis. We then examined its in vitro effect on H. pylori-induced interleukin (IL)-8 production in MKN28 gastric epithelial cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1083-4389
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
130-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:15068414-Anti-Ulcer Agents, pubmed-meshheading:15068414-Biopsy, pubmed-meshheading:15068414-Cell Line, pubmed-meshheading:15068414-Diterpenes, pubmed-meshheading:15068414-Epithelial Cells, pubmed-meshheading:15068414-Female, pubmed-meshheading:15068414-Gastric Mucosa, pubmed-meshheading:15068414-Gastritis, pubmed-meshheading:15068414-Helicobacter Infections, pubmed-meshheading:15068414-Helicobacter pylori, pubmed-meshheading:15068414-Histamine H2 Antagonists, pubmed-meshheading:15068414-Humans, pubmed-meshheading:15068414-Interleukin-8, pubmed-meshheading:15068414-Male, pubmed-meshheading:15068414-Middle Aged, pubmed-meshheading:15068414-Neutrophil Infiltration, pubmed-meshheading:15068414-Nizatidine, pubmed-meshheading:15068414-Pepsinogen A, pubmed-meshheading:15068414-Pepsinogen C, pubmed-meshheading:15068414-Sucralfate, pubmed-meshheading:15068414-Urease
pubmed:year
2004
pubmed:articleTitle
Teprenone, but not H2-receptor blocker or sucralfate, suppresses corpus Helicobacter pylori colonization and gastritis in humans: teprenone inhibition of H. pylori-induced interleukin-8 in MKN28 gastric epithelial cell lines.
pubmed:affiliation
Third Department of Internal Medicine, Department of Pathology, Tokyo, Japan.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial