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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2004-4-5
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pubmed:abstractText |
In a randomized, double-blind, crossover design, we compared the efficacy of sildenafil with placebo in patients with primary pulmonary hypertension (PPH). The primary end point was the change in exercise time on treadmill using the Naughton protocol. Secondary end points were change in cardiac index and pulmonary artery systolic pressure as assessed by Doppler echocardiography and quality of life (QOL) as assessed by a questionnaire.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0735-1097
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
7
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1149-53
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15063421-Adolescent,
pubmed-meshheading:15063421-Adult,
pubmed-meshheading:15063421-Aged,
pubmed-meshheading:15063421-Cardiac Volume,
pubmed-meshheading:15063421-Child,
pubmed-meshheading:15063421-Cross-Over Studies,
pubmed-meshheading:15063421-Double-Blind Method,
pubmed-meshheading:15063421-Echocardiography, Doppler,
pubmed-meshheading:15063421-Exercise Test,
pubmed-meshheading:15063421-Female,
pubmed-meshheading:15063421-Follow-Up Studies,
pubmed-meshheading:15063421-Humans,
pubmed-meshheading:15063421-Hypertension, Pulmonary,
pubmed-meshheading:15063421-Male,
pubmed-meshheading:15063421-Middle Aged,
pubmed-meshheading:15063421-Phosphodiesterase Inhibitors,
pubmed-meshheading:15063421-Piperazines,
pubmed-meshheading:15063421-Pulmonary Wedge Pressure,
pubmed-meshheading:15063421-Purines,
pubmed-meshheading:15063421-Quality of Life,
pubmed-meshheading:15063421-Sulfones,
pubmed-meshheading:15063421-Systole,
pubmed-meshheading:15063421-Treatment Outcome,
pubmed-meshheading:15063421-Vasodilator Agents
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pubmed:year |
2004
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pubmed:articleTitle |
Clinical efficacy of sildenafil in primary pulmonary hypertension: a randomized, placebo-controlled, double-blind, crossover study.
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pubmed:affiliation |
Department of Cardiology, CARE Hospital, Hyderabad, India. bkssastry@hotmail.com
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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