Linked Life Data

14984800

Source:http://linkedlifedata.com/resource/pubmed/id/14984800

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2004-2-26
pubmed:abstractText
Isatin is an endogenous indole present in mammalian tissues and fluids. This study was designed to test the effect of both acute stress (AS) and gender on isatin's levels in rat serum, heart and brain, using a HPLC-UV detection method. Basal brain isatin levels were higher in females than in males. AS resulted in increased isatin levels in male serum, heart and brain, and in female serum and heart, but not in the brain. The percentage increases were greater in males than in females in all three sources. After stress, there were significant correlations between isatin levels in the serum and the heart. However, there were no correlations between brain levels and those in the other sources. These results consolidate previous evidence that isatin levels are altered by stress and suggest that brain isatin is under separate control from that in the periphery.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0031-9384
pubmed:author
pubmed:issnType
Print
pubmed:volume
80
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
665-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Effect of acute stress and gender on isatin in rat tissues and serum.
pubmed:affiliation
Department of Biology, University of Saratov, Astrakhanskaya Str. 83, 410026 Saratov, Russia. n.igosheva@imperial.ac.uk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't