Linked Life Data

14969051

Source:http://linkedlifedata.com/resource/pubmed/id/14969051

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5 Suppl 31
pubmed:dateCreated
2004-2-18
pubmed:abstractText
The progression of rheumatoid arthritis (RA), a disease characterized by synovitis, cartilage degradation and bone erosion, is highly variable from patient to patient. New specific biological markers reflecting quantitative and dynamic changes in joint tissue turnover have been recently developed and include assays for type II collagen synthesis and degradation and synovitis. Increasing evidence from prospective studies in early RA indicate that some of these markers may be useful to predict the progression and identify patients at risk for rapid joint damage, before any damage is detected by radiography. Although studies on their value in assessing the efficacy of treatments are still limited, preliminary data in early RA suggest that biological markers will play an important role in the development and the early monitoring of disease modifying antirheumatic drugs with respect to future radiographic progression.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0392-856X
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S54-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Biochemical markers of joint tissue turnover in early rheumatoid arthritis.
pubmed:affiliation
University Hospital Maastricht, Maastricht, The Netherlands. patrick.garnero@synarc.com
pubmed:publicationType
Journal Article, Comparative Study, Review