Source:http://linkedlifedata.com/resource/pubmed/id/14743150
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-1-26
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pubmed:abstractText |
Although current treatments for restenosis attempt to prevent the development of intimal hyperplasia, an alternative strategy is to induce intimal atrophy after restenosis has developed. Because platelet-derived growth factor (PDGF) is a smooth muscle cell growth and survival factor, we tested the hypothesis that complete blockade of PDGF by using antibodies against PDGF receptors alpha and beta would cause intimal atrophy in a baboon vascular graft model.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0741-5214
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
440-6
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:14743150-Animals,
pubmed-meshheading:14743150-Atrophy,
pubmed-meshheading:14743150-Blood Vessel Prosthesis,
pubmed-meshheading:14743150-Graft Occlusion, Vascular,
pubmed-meshheading:14743150-Male,
pubmed-meshheading:14743150-Papio,
pubmed-meshheading:14743150-Polytetrafluoroethylene,
pubmed-meshheading:14743150-Receptor, Platelet-Derived Growth Factor alpha,
pubmed-meshheading:14743150-Receptor, Platelet-Derived Growth Factor beta,
pubmed-meshheading:14743150-Tunica Intima
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pubmed:year |
2004
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pubmed:articleTitle |
Concomitant blockade of platelet-derived growth factor receptors alpha and beta induces intimal atrophy in baboon PTFE grafts.
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pubmed:affiliation |
Department of Surgery, University of Washington Medical Center, Seattle, WA 98195, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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