rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
2004-1-22
|
pubmed:abstractText |
Glomerular endothelial cells play a role in the pathogenesis of glomerulonephritis by producing chemotactic factors. We investigated the role of NF-kappa B and AP-1 in tumour necrosis factor alpha (TNF-alpha) induced monocyte chemoattractant protein 1 (MCP-1) production in cultured human glomerular endothelial cells (HGEC). We also examined whether or not these processes could be modified by glucocorticoid.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0931-0509
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
19
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
312-9
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14736953-Base Sequence,
pubmed-meshheading:14736953-Blotting, Northern,
pubmed-meshheading:14736953-Blotting, Western,
pubmed-meshheading:14736953-Cells, Cultured,
pubmed-meshheading:14736953-Chemokine CCL2,
pubmed-meshheading:14736953-Dexamethasone,
pubmed-meshheading:14736953-Down-Regulation,
pubmed-meshheading:14736953-Drug Interactions,
pubmed-meshheading:14736953-Endothelium, Vascular,
pubmed-meshheading:14736953-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:14736953-Humans,
pubmed-meshheading:14736953-Kidney Glomerulus,
pubmed-meshheading:14736953-Molecular Sequence Data,
pubmed-meshheading:14736953-NF-kappa B,
pubmed-meshheading:14736953-Polymerase Chain Reaction,
pubmed-meshheading:14736953-RNA, Messenger,
pubmed-meshheading:14736953-Reference Values,
pubmed-meshheading:14736953-Sensitivity and Specificity,
pubmed-meshheading:14736953-Transcription Factor AP-1,
pubmed-meshheading:14736953-Tumor Necrosis Factor-alpha
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pubmed:year |
2004
|
pubmed:articleTitle |
Dexamethasone regulates AP-1 to repress TNF-alpha induced MCP-1 production in human glomerular endothelial cells.
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pubmed:affiliation |
Department of Internal Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. skpark@www.amc.seoul.kr
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|