rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2004-1-12
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pubmed:abstractText |
Currently prostate-specific membrane antigen (PSMA) is showing promise both as an imaging and therapeutic target for occult prostate cancer metastases. First generation antibodies against PSMA are used for the FDA approved Prostascint trade mark monoclonal antibody scan and second generation antibodies are being developed for therapeutic targeting as well as imaging 1. However, there have been reports describing PSMA expression in non-prostatic tissues including kidney, liver, and brain. As we had previously showed the existence of a human PSMA homolog, we set out to determine if this non-prostatic expression was due to expression of the PSMA or another gene.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Capromab Pendetide,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Complementary,
http://linkedlifedata.com/resource/pubmed/chemical/Glutamate Carboxypeptidase II,
http://linkedlifedata.com/resource/pubmed/chemical/Indium Radioisotopes,
http://linkedlifedata.com/resource/pubmed/chemical/glutamate carboxypeptidase II, human
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0270-4137
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2003 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
200-10
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:14716746-Antibodies, Monoclonal,
pubmed-meshheading:14716746-Antigens, Surface,
pubmed-meshheading:14716746-Base Sequence,
pubmed-meshheading:14716746-Blotting, Northern,
pubmed-meshheading:14716746-Chromosome Mapping,
pubmed-meshheading:14716746-Chromosomes, Human, Pair 11,
pubmed-meshheading:14716746-DNA, Complementary,
pubmed-meshheading:14716746-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:14716746-Glutamate Carboxypeptidase II,
pubmed-meshheading:14716746-Humans,
pubmed-meshheading:14716746-Indium Radioisotopes,
pubmed-meshheading:14716746-Male,
pubmed-meshheading:14716746-Molecular Sequence Data,
pubmed-meshheading:14716746-Prostatic Neoplasms,
pubmed-meshheading:14716746-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2004
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pubmed:articleTitle |
Comparative analysis of prostate-specific membrane antigen (PSMA) versus a prostate-specific membrane antigen-like gene.
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pubmed:affiliation |
The Department of Urology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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