|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
2004-1-2
|
|
pubmed:abstractText |
Leukotrienes are inflammatory mediators generated from arachidonic acid (polyunsaturated n-6 fatty acid) by the enzyme 5-lipoxygenase. Since atherosclerosis involves arterial inflammation, we hypothesized that a polymorphism in the 5-lipoxygenase gene promoter could relate to atherosclerosis in humans and that this effect could interact with the dietary intake of competing 5-lipoxygenase substrates.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
1533-4406
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright 2004 Massachusetts Medical Society
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
1
|
|
pubmed:volume |
350
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
29-37
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:14702425-Adult,
pubmed-meshheading:14702425-Arachidonate 5-Lipoxygenase,
pubmed-meshheading:14702425-Arteriosclerosis,
pubmed-meshheading:14702425-Carotid Arteries,
pubmed-meshheading:14702425-Cholesterol, LDL,
pubmed-meshheading:14702425-Diet,
pubmed-meshheading:14702425-Fatty Acids,
pubmed-meshheading:14702425-Female,
pubmed-meshheading:14702425-Genotype,
pubmed-meshheading:14702425-Humans,
pubmed-meshheading:14702425-Inflammation,
pubmed-meshheading:14702425-Logistic Models,
pubmed-meshheading:14702425-Male,
pubmed-meshheading:14702425-Middle Aged,
pubmed-meshheading:14702425-Multivariate Analysis,
pubmed-meshheading:14702425-Polymorphism, Genetic,
pubmed-meshheading:14702425-Risk Factors,
pubmed-meshheading:14702425-Tunica Intima,
pubmed-meshheading:14702425-Tunica Media
|
|
pubmed:year |
2004
|
|
pubmed:articleTitle |
Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis.
|
|
pubmed:affiliation |
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, CA 91803-8000, USA. jimdwye@usc.edu
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|
