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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2003-12-31
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pubmed:abstractText |
Inappropriate coping with chronic stress may result in a state of "vital exhaustion" that has been associated with coronary artery disease. Impaired fibrinolysis due to an increase in type 1 plasminogen activator inhibitor (PAI-1) might mediate this link. Genetic and environmental factors both regulate the plasma PAI-1 levels. We investigated the contribution of the PAI-1 4G/5G gene polymorphism to the plasma levels of PAI-1 in exhaustion.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1129-471X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
791-6
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:14699709-Adult,
pubmed-meshheading:14699709-Biological Markers,
pubmed-meshheading:14699709-Blood Pressure,
pubmed-meshheading:14699709-Body Constitution,
pubmed-meshheading:14699709-Cardiovascular Diseases,
pubmed-meshheading:14699709-Cholesterol, HDL,
pubmed-meshheading:14699709-Cholesterol, LDL,
pubmed-meshheading:14699709-Cohort Studies,
pubmed-meshheading:14699709-Fatigue,
pubmed-meshheading:14699709-Female,
pubmed-meshheading:14699709-Fibrinolysis,
pubmed-meshheading:14699709-Gene Frequency,
pubmed-meshheading:14699709-Genetic Predisposition to Disease,
pubmed-meshheading:14699709-Genotype,
pubmed-meshheading:14699709-Germany,
pubmed-meshheading:14699709-Hemoglobin A, Glycosylated,
pubmed-meshheading:14699709-Humans,
pubmed-meshheading:14699709-Male,
pubmed-meshheading:14699709-Middle Aged,
pubmed-meshheading:14699709-Plasminogen Activator Inhibitor 1,
pubmed-meshheading:14699709-Polymorphism, Genetic,
pubmed-meshheading:14699709-Risk Factors,
pubmed-meshheading:14699709-Serine Proteinase Inhibitors,
pubmed-meshheading:14699709-Severity of Illness Index,
pubmed-meshheading:14699709-Statistics as Topic
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pubmed:year |
2003
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pubmed:articleTitle |
Contribution of the type 1 plasminogen activator inhibitor 4G/5G gene polymorphism to impaired fibrinolysis in vital exhaustion.
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pubmed:affiliation |
Institute for Behavioral Sciences, Swiss Federal Institute of Technology, University Hospital, Zürich, Switzerland. roland.vonkaenel@ifv.gess.etzh.ch
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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