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pubmed-article:14695158pubmed:abstractTextWe evaluated the expression of platelet-derived growth factor (PDGF) ligands and receptors in clinical specimens of human pancreatic adenocarcinomas and determined the therapeutic effect of STI571 (Gleevec), a protein tyrosine kinase inhibitor of PDGF receptor (PDGFR), on human pancreatic carcinoma cells growing in the pancreas and liver of nude mice.lld:pubmed
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pubmed-article:14695158pubmed:articleTitleInhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model.lld:pubmed
pubmed-article:14695158pubmed:affiliationDepartment of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.lld:pubmed
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