Linked Life Data

14578097

Source:http://linkedlifedata.com/resource/pubmed/id/14578097

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2003-10-27
pubmed:abstractText
Cord blood (CB) has been used as an alternative source of transplantable allogeneic stem cells for a variety of malignant and non-malignant diseases. However, we have demonstrated delayed recovery of T- and B-cell function, and T-cell subsets post unrelated CB transplantation (UCBT), and deficiencies of CB mononuclear cells (MNC) in producing cytokines, including G-CSF, GM-CSF, M-CSF, IL-12, and IL-15. In this study we have investigated the ex vivo generation of DC from CB versus mobilized adult peripheral blood (APB) for later use as adoptive cellular immunotherapy.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1465-3249
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
349-61
pubmed:dateRevised
2008-4-24
pubmed:meshHeading
pubmed-meshheading:14578097-Adult, pubmed-meshheading:14578097-Antigens, Surface, pubmed-meshheading:14578097-B-Lymphocytes, pubmed-meshheading:14578097-Cell Adhesion, pubmed-meshheading:14578097-Cell Differentiation, pubmed-meshheading:14578097-Cells, Cultured, pubmed-meshheading:14578097-Cord Blood Stem Cell Transplantation, pubmed-meshheading:14578097-Culture Techniques, pubmed-meshheading:14578097-Cytokines, pubmed-meshheading:14578097-Dendritic Cells, pubmed-meshheading:14578097-Fetal Blood, pubmed-meshheading:14578097-Growth Substances, pubmed-meshheading:14578097-Hematopoietic Stem Cell Mobilization, pubmed-meshheading:14578097-Humans, pubmed-meshheading:14578097-Immunotherapy, pubmed-meshheading:14578097-Infant, Newborn, pubmed-meshheading:14578097-Leukocytes, Mononuclear, pubmed-meshheading:14578097-Recovery of Function, pubmed-meshheading:14578097-T-Lymphocytes, pubmed-meshheading:14578097-Transplantation, Homologous
pubmed:year
2003
pubmed:articleTitle
A comparison of ex vivo expanded DCs derived from cord blood and mobilized adult peripheral blood plastic-adherent mononuclear cells: decreased alloreactivity of cord blood DCs.
pubmed:affiliation
Department of Pediatrics and Lombardi Cancer Center, Georgetown University Hospital, Washington, DC, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't