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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2003-10-23
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pubmed:abstractText |
We evaluated the effect of vaccination with the SAG1 protein of Toxoplasma gondii against congenital toxoplasmosis in mice with different genetic backgrounds. In BALB/c mice (H-2(d)), vaccination reduced the number of infected fetuses by 50% and was associated with a mixed type 1 and type 2 immunity. In CBA/J mice (H-2(k)), vaccination increased the number of infected fetuses by 50% and was associated with a predominant type 2 response. Our results indicate that the effect of vaccination with SAG1 is controlled by the genetic background of the mouse.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-10320624,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-10608781,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-10639474,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-10948109,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-11179334,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-11285480,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-11574666,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-11578086,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-12389596,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-12490084,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-1614736,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-1670604,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-1783431,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-1926725,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-1940349,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-1940350,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-3128869,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-3183382,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-3346545,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-3493977,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-3528317,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-6631778,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-6833761,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-6863940,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-7682587,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-7722286,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-7887016,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-8086543,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-8168967,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-8791694,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-8897506,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-9119459,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-9682392,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14573684-9712808
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0019-9567
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6615-9
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:14573684-Animals,
pubmed-meshheading:14573684-Antibodies, Protozoan,
pubmed-meshheading:14573684-Antigens, Protozoan,
pubmed-meshheading:14573684-Cytokines,
pubmed-meshheading:14573684-Female,
pubmed-meshheading:14573684-Immunization,
pubmed-meshheading:14573684-Infectious Disease Transmission, Vertical,
pubmed-meshheading:14573684-Male,
pubmed-meshheading:14573684-Mice,
pubmed-meshheading:14573684-Mice, Inbred BALB C,
pubmed-meshheading:14573684-Mice, Inbred CBA,
pubmed-meshheading:14573684-Protozoan Proteins,
pubmed-meshheading:14573684-Protozoan Vaccines,
pubmed-meshheading:14573684-Species Specificity,
pubmed-meshheading:14573684-Toxoplasma,
pubmed-meshheading:14573684-Toxoplasmosis, Congenital,
pubmed-meshheading:14573684-Vaccination
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pubmed:year |
2003
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pubmed:articleTitle |
Vaccination with Toxoplasma gondii SAG-1 protein is protective against congenital toxoplasmosis in BALB/c mice but not in CBA/J mice.
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pubmed:affiliation |
Institut de Parasitologie et de Pathologie Tropicale, INSERM U 392, Faculté de Médecine, Université de Strasbourg, 67000 Strasbourg, France. valerie.letscher@medecine.u-strasbg.fr
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pubmed:publicationType |
Journal Article
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