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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2003-10-13
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pubmed:abstractText |
CA 19-9, equivalent to Sialyl Lewis antigen, is a well-known tumor marker in pancreatic cancer. At the initial step of the biosynthesis of CA 19-9, N-acetylglucosamine-beta1,3-galactosyltransferase (beta3Gal-T) transfers galactose to N-acetylglucosamine (GlcNAc). Recently, beta3Gal-T5 has been presumed to be related to the formation of the type 1 chain in an in vitro experiment in terms of kinetic enzyme characterization. The purpose of this study was to investigate which beta3Gal-T is related to the synthesis of CA 19-9 in human pancreatic cancer tissues.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1015-2008
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2004 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
26-34
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14555842-Aged,
pubmed-meshheading:14555842-Antigens, Neoplasm,
pubmed-meshheading:14555842-CA-19-9 Antigen,
pubmed-meshheading:14555842-Female,
pubmed-meshheading:14555842-Galactosyltransferases,
pubmed-meshheading:14555842-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:14555842-Humans,
pubmed-meshheading:14555842-Immunohistochemistry,
pubmed-meshheading:14555842-Male,
pubmed-meshheading:14555842-Middle Aged,
pubmed-meshheading:14555842-Pancreatic Neoplasms,
pubmed-meshheading:14555842-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:14555842-RNA, Messenger,
pubmed-meshheading:14555842-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2004
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pubmed:articleTitle |
Association between expression levels of CA 19-9 and N-acetylglucosamine-beta;1,3-galactosyltransferase 5 gene in human pancreatic cancer tissue.
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pubmed:affiliation |
Department of Surgery and Clinical Oncology, Graduate School of Medicine, Osaka University, Osaka, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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