Source:http://linkedlifedata.com/resource/pubmed/id/14499674
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
2003-9-22
|
pubmed:abstractText |
Neutral Endopeptidase (NEP) is a cell surface enzyme that cleaves and inactivates neuropeptides. When present on androgen-dependent prostate cancer (PC) cells, NEP inactivates growth stimulatory neuropeptides. After androgen ablation NEP expression decreases and neuropeptides can enhance cell growth, leading to the development of androgen-independent, neuropeptide stimulated PC. Aim of the study was to analyse the expression, localisation and distribution of NEP in benign and malignant prostatic tissues and its relation to the cytoskeleton.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0302-2838
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
44
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
415-22
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:14499674-Cytoskeleton,
pubmed-meshheading:14499674-Humans,
pubmed-meshheading:14499674-Immunohistochemistry,
pubmed-meshheading:14499674-Male,
pubmed-meshheading:14499674-Neprilysin,
pubmed-meshheading:14499674-Prostatic Hyperplasia,
pubmed-meshheading:14499674-Prostatic Neoplasms
|
pubmed:year |
2003
|
pubmed:articleTitle |
Expression and immunolocalisation of neutral endopeptidase in prostate cancer.
|
pubmed:affiliation |
Department of Anatomy and Cell Biology, Philipps-University, Marburg, Germany. m.albrecht@lrz.uni.muenchen.de
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|