Source:http://linkedlifedata.com/resource/umls/id/C0025250
MSH: Enzyme that is a major constituent of kidney brush-border membranes and is also present to a lesser degree in the brain and other tissues. It preferentially catalyzes cleavage at the amino group of hydrophobic residues of the B-chain of insulin as well as opioid peptides and other biologically active peptides. The enzyme is inhibited primarily by EDTA, phosphoramidon, and thiorphan and is reactivated by zinc. Neprilysin is identical to common acute lymphoblastic leukemia antigen (CALLA Antigen), an important marker in the diagnosis of human acute lymphocytic leukemia. There is no relationship with CALLA PLANT.,NCI: A cell-surface enzyme found on prostate epithelial cells. It can inhibit cell migration of prostate cancer cells, probably by disrupting focal adhesion kinase phosphorylation. (from J Clin Invest 2000;106:1399-1407 via Medscape),NCI: Abundant in the kidney proximal tubule brush border and glomerular epithelium, but expressed in a variety of tissues by human MME Gene (M13 Peptidase Family), 749