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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1992-12-17
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pubmed:abstractText |
The aim of the study was to use a novel combination of two methods for the simultaneous evaluation of two effects of oral cisapride in 10 diabetic patients with autonomic neuropathy; gastric empyting time was measured by following radio-opaque markers and orocaecal transit time by the sulphasalazine-sulphapridine method. The study was of double-blind, randomized, placebo-controlled, cross-over design. It was possible to evaluate the effect of a prokinetic drug on gastric emptying and orocaecal transit times using these two noninvasive techniques at the same time. Cisapride significantly reduced both the gastric empyting (1.2 h versus 2.1 h) and orocaecal tansit (5.9 h versus 7.7 h) times.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0031-6970
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
121-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1425866-Adult,
pubmed-meshheading:1425866-Aged,
pubmed-meshheading:1425866-Autonomic Nervous System Diseases,
pubmed-meshheading:1425866-Cisapride,
pubmed-meshheading:1425866-Diabetic Neuropathies,
pubmed-meshheading:1425866-Double-Blind Method,
pubmed-meshheading:1425866-Female,
pubmed-meshheading:1425866-Gastric Emptying,
pubmed-meshheading:1425866-Gastrointestinal Transit,
pubmed-meshheading:1425866-Humans,
pubmed-meshheading:1425866-Male,
pubmed-meshheading:1425866-Middle Aged,
pubmed-meshheading:1425866-Piperidines,
pubmed-meshheading:1425866-Serotonin Antagonists,
pubmed-meshheading:1425866-Time Factors
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pubmed:year |
1992
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pubmed:articleTitle |
Simultaneous noninvasive evaluation of gastric emptying and orocaecal transit times. Use in studying the actions of cisapride in diabetic patients.
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pubmed:affiliation |
Therapeutic Research Unit, Lariboisière Hospital, Paris, France.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|