Source:http://linkedlifedata.com/resource/pubmed/id/14232193
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1965-3-1
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pubmed:abstractText |
Sulfaphenazole (Orisul), which had been reported to cause a convulsant syndrome in young European children, lowered the electroshock threshold in rats when administered in the form of tablets or suspension. This effect was not obtained with a sample of sulfaphenazole pure drug or with several other long-acting oral sulfonamide preparations, but was obtained with a mixture of impurities which had been found in the same lot of Orisul that had reportedly caused the convulsant syndrome. A change in the method of manufacture now provides a product which is free from these impurities.
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pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/CENTRAL NERVOUS SYSTEM,
http://linkedlifedata.com/resource/pubmed/keyword/EXPERIMENTAL LAB STUDY,
http://linkedlifedata.com/resource/pubmed/keyword/PHARMACOLOGY,
http://linkedlifedata.com/resource/pubmed/keyword/RATS,
http://linkedlifedata.com/resource/pubmed/keyword/SULFAPHENAZOLE,
http://linkedlifedata.com/resource/pubmed/keyword/SULFONAMIDES
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
OM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0008-4409
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
23
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
180-1
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pubmed:dateRevised |
2010-6-22
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pubmed:meshHeading | |
pubmed:year |
1965
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pubmed:articleTitle |
STIMULANT EFFECTS OF A SULFONAMIDE PREPARATION, SULFAPHENAZOLE, ON THE CENTRAL NERVOUS SYSTEM IN RATS.
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pubmed:publicationType |
Journal Article
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