| pubmed-article:1384114 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1384114 | lifeskim:mentions | umls-concept:C0021758 | lld:lifeskim |
| pubmed-article:1384114 | lifeskim:mentions | umls-concept:C0225336 | lld:lifeskim |
| pubmed-article:1384114 | lifeskim:mentions | umls-concept:C1518997 | lld:lifeskim |
| pubmed-article:1384114 | lifeskim:mentions | umls-concept:C0001511 | lld:lifeskim |
| pubmed-article:1384114 | lifeskim:mentions | umls-concept:C1456820 | lld:lifeskim |
| pubmed-article:1384114 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:1384114 | lifeskim:mentions | umls-concept:C1704259 | lld:lifeskim |
| pubmed-article:1384114 | lifeskim:mentions | umls-concept:C1705987 | lld:lifeskim |
| pubmed-article:1384114 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:1384114 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:1384114 | pubmed:dateCreated | 1992-10-30 | lld:pubmed |
| pubmed-article:1384114 | pubmed:abstractText | We demonstrated that tumour necrosis factor alpha (TNF-alpha) and interleukin 4 (IL-4) increased endothelial cell (EC) adhesiveness for peripheral blood lymphocytes (PBL) by promoting transcription and protein synthesis. The different kinetics observed with TNF-alpha and IL-4 suggest the involvement of different adhesion molecules. Blocking adhesion assays and immunofluorescence analysis showed that PBL adhesion to endothelial cells involves different pair adhesion molecules. Whereas IL-4 promoted an LFA-1-dependent/ICAM-1-independent adhesion pathway on EC, TNF-alpha stimulated an LFA-1-dependent/ICAM-1-dependent adhesion pathway on EC. In contrast, VLA-4/VCAM-1 molecules were involved in PBL adhesion both to IL-4 and to TNF-alpha-stimulated EC. Finally, we found that a CD2-dependent/LFA-3-independent adhesion pathway was mainly involved in IL-4-stimulated EC. | lld:pubmed |
| pubmed-article:1384114 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1384114 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1384114 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1384114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:1384114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1384114 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1384114 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:1384114 | pubmed:issn | 0300-9475 | lld:pubmed |
| pubmed-article:1384114 | pubmed:author | pubmed-author:ThibaultGG | lld:pubmed |
| pubmed-article:1384114 | pubmed:author | pubmed-author:BardosPP | lld:pubmed |
| pubmed-article:1384114 | pubmed:author | pubmed-author:LebranchuYY | lld:pubmed |
| pubmed-article:1384114 | pubmed:author | pubmed-author:GaléaPP | lld:pubmed |
| pubmed-article:1384114 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1384114 | pubmed:volume | 36 | lld:pubmed |
| pubmed-article:1384114 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1384114 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1384114 | pubmed:pagination | 575-85 | lld:pubmed |
| pubmed-article:1384114 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:1384114 | pubmed:meshHeading | pubmed-meshheading:1384114-... | lld:pubmed |
| pubmed-article:1384114 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1384114 | pubmed:articleTitle | Interleukin 4 and tumour necrosis factor alpha induce different adhesion pathways in endothelial cells for the binding of peripheral blood lymphocytes. | lld:pubmed |
| pubmed-article:1384114 | pubmed:affiliation | Laboratoire d'Immunologie, CHU Bretonneau, Université de Tours, France. | lld:pubmed |
| pubmed-article:1384114 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1384114 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1384114 | lld:pubmed |
