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rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0004561,
umls-concept:C0005953,
umls-concept:C0026809,
umls-concept:C0037993,
umls-concept:C0085110,
umls-concept:C0085243,
umls-concept:C0086418,
umls-concept:C0162371,
umls-concept:C0205245,
umls-concept:C0229664,
umls-concept:C0332835,
umls-concept:C0456148,
umls-concept:C0751781,
umls-concept:C0882849,
umls-concept:C1413227,
umls-concept:C1417753
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pubmed:issue |
9
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|
pubmed:dateCreated |
2003-9-9
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|
pubmed:abstractText |
Human CD5+ B cells are the major B cell subset in fetal spleen and umbilical cord blood (CB), and their number gradually diminishes in both spleen and peripheral blood from infancy through childhood while conventional B cells increase. In this study, we investigated whether CD5+ cells differentiate from adult hematopoietic stem cells (HSCs) as well as fetal ones in immunodeficient mice.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0301-472X
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pubmed:author |
pubmed-author:AndoKiyoshiK,
pubmed-author:HabuSonokoS,
pubmed-author:HiranoYasuyukiY,
pubmed-author:ItoMamoruM,
pubmed-author:ItoRyojiR,
pubmed-author:KametaniYoshieY,
pubmed-author:KatanoIkumiI,
pubmed-author:KatoShunichiS,
pubmed-author:MatsumuraTakuyaT,
pubmed-author:MotoyoshiKazuoK,
pubmed-author:SaitoYukiY,
pubmed-author:ShiinaMasashiM,
pubmed-author:TokudaYutakaY,
pubmed-author:TsukamotoHideoH
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pubmed:issnType |
Print
|
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pubmed:volume |
31
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
789-97
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pubmed:dateRevised |
2010-3-23
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pubmed:meshHeading |
pubmed-meshheading:12962725-Animals,
pubmed-meshheading:12962725-Antigens, CD34,
pubmed-meshheading:12962725-Antigens, CD5,
pubmed-meshheading:12962725-B-Lymphocytes,
pubmed-meshheading:12962725-Bone Marrow Cells,
pubmed-meshheading:12962725-Cell Differentiation,
pubmed-meshheading:12962725-Cell Lineage,
pubmed-meshheading:12962725-Fetal Blood,
pubmed-meshheading:12962725-Mice,
pubmed-meshheading:12962725-Mice, Inbred NOD,
pubmed-meshheading:12962725-Mice, SCID,
pubmed-meshheading:12962725-Spleen,
pubmed-meshheading:12962725-Stem Cell Transplantation,
pubmed-meshheading:12962725-Transplantation, Heterologous
|
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pubmed:year |
2003
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pubmed:articleTitle |
Functional CD5+ B cells develop predominantly in the spleen of NOD/SCID/gammac(null) (NOG) mice transplanted either with human umbilical cord blood, bone marrow, or mobilized peripheral blood CD34+ cells.
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pubmed:affiliation |
Third Department of Internal Medicine, National Defense Medical College, Saitama, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
