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pubmed-article:12940778pubmed:abstractTextOvarian granulosa cell tumour (OGCT) is a sex-cord stromal tumour with a general trend toward late relapse and/or metastasis. However, mortality rate corrected for long-term follow-up shows that about 50% of patients die within 20 years of diagnosis. Classical clinicopathological parameters are unable to predict the biological behaviour of OGCT. The involvement of a recently characterized subtype of oestrogen receptor, ERbeta, in ovarian carcinogenesis has been hypothesized.lld:pubmed
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pubmed-article:12940778pubmed:articleTitleLoss of oestrogen receptor beta, high PCNA and p53 expression and aneuploidy as markers of worse prognosis in ovarian granulosa cell tumours.lld:pubmed
pubmed-article:12940778pubmed:affiliationDepartment of Biomorphological and Functional Sciences, University 'Federico II' of Naples, Naples, Italy. amando.tedeschi@virgilio.itlld:pubmed
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