|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0002938,
umls-concept:C0017262,
umls-concept:C0018206,
umls-concept:C0018207,
umls-concept:C0033325,
umls-concept:C0034804,
umls-concept:C0072108,
umls-concept:C0079419,
umls-concept:C0185117,
umls-concept:C0330390,
umls-concept:C1457868,
umls-concept:C1517945,
umls-concept:C2745888,
umls-concept:C2911684
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2003-8-27
|
|
pubmed:abstractText |
Ovarian granulosa cell tumour (OGCT) is a sex-cord stromal tumour with a general trend toward late relapse and/or metastasis. However, mortality rate corrected for long-term follow-up shows that about 50% of patients die within 20 years of diagnosis. Classical clinicopathological parameters are unable to predict the biological behaviour of OGCT. The involvement of a recently characterized subtype of oestrogen receptor, ERbeta, in ovarian carcinogenesis has been hypothesized.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0309-0167
|
|
pubmed:author |
pubmed-author:ChieffoVV,
pubmed-author:De RosaGG,
pubmed-author:ErricoM EME,
pubmed-author:FrancoRR,
pubmed-author:MansuetoGG,
pubmed-author:MezzaEE,
pubmed-author:NappiCC,
pubmed-author:PasqualiDD,
pubmed-author:SinisiAA,
pubmed-author:SommoFF,
pubmed-author:StaibanoSS,
pubmed-author:TremolaterraFF
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
43
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
254-62
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:12940778-Adolescent,
pubmed-meshheading:12940778-Adult,
pubmed-meshheading:12940778-Aneuploidy,
pubmed-meshheading:12940778-DNA, Neoplasm,
pubmed-meshheading:12940778-Estrogen Receptor beta,
pubmed-meshheading:12940778-Female,
pubmed-meshheading:12940778-Granulosa Cell Tumor,
pubmed-meshheading:12940778-Humans,
pubmed-meshheading:12940778-Immunohistochemistry,
pubmed-meshheading:12940778-Infant,
pubmed-meshheading:12940778-Middle Aged,
pubmed-meshheading:12940778-Ovarian Neoplasms,
pubmed-meshheading:12940778-Prognosis,
pubmed-meshheading:12940778-Proliferating Cell Nuclear Antigen,
pubmed-meshheading:12940778-Receptors, Estrogen,
pubmed-meshheading:12940778-Tumor Markers, Biological,
pubmed-meshheading:12940778-Tumor Suppressor Protein p53
|
|
pubmed:year |
2003
|
|
pubmed:articleTitle |
Loss of oestrogen receptor beta, high PCNA and p53 expression and aneuploidy as markers of worse prognosis in ovarian granulosa cell tumours.
|
|
pubmed:affiliation |
Department of Biomorphological and Functional Sciences, University 'Federico II' of Naples, Naples, Italy. amando.tedeschi@virgilio.it
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
