Source:http://linkedlifedata.com/resource/pubmed/id/12925980
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2003-8-19
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pubmed:abstractText |
The demonstration of the monoclonality of immunoglobulin heavy chain (IgH) gene rearrangement is an indispensable method for the diagnosis of B-cell lymphoma as well as histocytochemical analysis. For the detection of IgH gene rearrangement, the extraction of DNA from a homogenous cell population is necessary. Recently, the laser capture microdissection (LCM) technique was shown to isolate specific cells from histopathologic specimens for molecular analysis. However, to the authors' knowledge the applicability of LCM to cytologic specimens has not yet been well established.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2003 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
25
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pubmed:volume |
99
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
198-204
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:12925980-Aged,
pubmed-meshheading:12925980-Aged, 80 and over,
pubmed-meshheading:12925980-Cell Biology,
pubmed-meshheading:12925980-Female,
pubmed-meshheading:12925980-Gene Rearrangement,
pubmed-meshheading:12925980-Humans,
pubmed-meshheading:12925980-Immunoglobulin Heavy Chains,
pubmed-meshheading:12925980-Lasers,
pubmed-meshheading:12925980-Lymphoma,
pubmed-meshheading:12925980-Male,
pubmed-meshheading:12925980-Middle Aged,
pubmed-meshheading:12925980-Polymerase Chain Reaction,
pubmed-meshheading:12925980-Polymorphism, Single-Stranded Conformational,
pubmed-meshheading:12925980-Sensitivity and Specificity,
pubmed-meshheading:12925980-Specimen Handling
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pubmed:year |
2003
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pubmed:articleTitle |
Application of laser capture microdissection to cytologic specimens for the detection of immunoglobulin heavy chain gene rearrangement in patients with malignant lymphoma.
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pubmed:affiliation |
Laboratory of Molecular and Cellular Pathology, Hokkaido University School of Medicine, Sapporo, Japan.
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pubmed:publicationType |
Journal Article,
Clinical Trial
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