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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2003-8-19
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pubmed:abstractText |
Destruction of cartilage in osteoarthritis is a direct effect of an imbalance between catabolic and anabolic activities in the tissue. While a great deal is known about catabolism, we sought to determine the biochemical basis of the anabolic activity.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0021-9355
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
85-A Suppl 3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
59-66
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pubmed:dateRevised |
2010-10-25
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pubmed:meshHeading |
pubmed-meshheading:12925611-Aged,
pubmed-meshheading:12925611-Aged, 80 and over,
pubmed-meshheading:12925611-Bone Morphogenetic Protein 2,
pubmed-meshheading:12925611-Bone Morphogenetic Proteins,
pubmed-meshheading:12925611-Cartilage, Articular,
pubmed-meshheading:12925611-Cell Differentiation,
pubmed-meshheading:12925611-Cells, Cultured,
pubmed-meshheading:12925611-Chondrocytes,
pubmed-meshheading:12925611-Female,
pubmed-meshheading:12925611-Gene Expression Regulation,
pubmed-meshheading:12925611-Humans,
pubmed-meshheading:12925611-Interleukin-1,
pubmed-meshheading:12925611-Male,
pubmed-meshheading:12925611-Middle Aged,
pubmed-meshheading:12925611-Osteoarthritis,
pubmed-meshheading:12925611-RNA, Messenger,
pubmed-meshheading:12925611-Transforming Growth Factor beta,
pubmed-meshheading:12925611-Tumor Necrosis Factor-alpha,
pubmed-meshheading:12925611-Up-Regulation
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pubmed:year |
2003
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pubmed:articleTitle |
Stimulation of BMP-2 expression by pro-inflammatory cytokines IL-1 and TNF-alpha in normal and osteoarthritic chondrocytes.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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