Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2003-8-13
pubmed:abstractText
In the framework of the Thyroid initiative Papillon 2001 - 2002 thyroid nodules and sonographically detectable focal lesions with a diameter more than 5 mm were verified in 23.1% of 64.123 persons without a history of thyroid disease. The frequency of such findings was with 33.0% in 46-65 years old persons three times higher then in persons aged 18-30 years (9.6%). In the diagnostic workup thyroid cancer was detected in 15 patients operated on up to now (6 women and 9 men; papillary cancers in 12 cases, follicular cancers in 3 cases) The smallest tumor had a diameter of 1.3 cm, the mean diameter was 2.3 +/- 91 cm. In 3 patients the tumor had invaded the tissue beyond the thyroid capsule, in 4 cases multicentric growth was detected. Lymph node metastases were found in 7/15 cases and distant metastases in 2/15 cases. These result reveal, that thyroid cancer detected by chance may be relatively aggressive. In daily routine, sonographically detectable lesions with poor echogenicity, irregular margins or internal calcifications with a diameter of more than 1 cm should be clarified by fine needle aspiration biopsy.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0020-9554
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
412-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:12914398-Adolescent, pubmed-meshheading:12914398-Adult, pubmed-meshheading:12914398-Age Factors, pubmed-meshheading:12914398-Aged, pubmed-meshheading:12914398-Biopsy, Needle, pubmed-meshheading:12914398-Cross-Sectional Studies, pubmed-meshheading:12914398-Female, pubmed-meshheading:12914398-Goiter, Endemic, pubmed-meshheading:12914398-Goiter, Nodular, pubmed-meshheading:12914398-Humans, pubmed-meshheading:12914398-Incidental Findings, pubmed-meshheading:12914398-Male, pubmed-meshheading:12914398-Mass Screening, pubmed-meshheading:12914398-Middle Aged, pubmed-meshheading:12914398-Neoplasm Staging, pubmed-meshheading:12914398-Occupational Health Services, pubmed-meshheading:12914398-Reproducibility of Results, pubmed-meshheading:12914398-Sex Factors, pubmed-meshheading:12914398-Thyroid Gland, pubmed-meshheading:12914398-Thyroid Neoplasms, pubmed-meshheading:12914398-Thyroid Nodule
pubmed:year
2003
pubmed:articleTitle
[Thyroid gland ultrasound screening (Papillon Initiative). Report of 15 incidentally detected thyroid cancers].
pubmed:affiliation
Klinik und Poliklinik für Nuklearmedizin, Universität Würzburg. Reiners_C@klinik.uni-wuerzburg.de
pubmed:publicationType
Journal Article, English Abstract, Multicenter Study