Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2003-7-24
pubmed:abstractText
The polarisation of the embryonic anteroposterior (AP) axis requires the establishment of positional cues with spatial information, and often involves complex intercellular communications, cell adhesion and cell movement. Recent work on several fronts has begun to shed light on how the initial asymmetries are established and maintained. In this review, I discuss the polarisation of the AP axis during Drosophila oogenesis, focusing on the function of the Notch signalling pathway and its relationship to the activation of the epidermal growth factor receptor. I make special reference to some aspects of Notch activity regulation during oogenesis that appear to depart from the canonical pathway. Finally, I hypothesise on possible similarities between these activities of Notch signalling during Drosophila oogenesis and vertebrate somitogenesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0265-9247
pubmed:author
pubmed:copyrightInfo
Copyright 2003 Wiley Periodicals, Inc.
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
781-91
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
The polarisation of the anteroposterior axis in Drosophila.
pubmed:affiliation
Howard Hughes Medical Institute, The Rockefeller University (Box 314) 1230 York Ave., New York, NY 10021, USA. lopezsh@rockvax.rockefeller.edu
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't