Linked Life Data

12841791

Source:http://linkedlifedata.com/resource/pubmed/id/12841791

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2003-7-4
pubmed:abstractText
CT based 3D treatment planning systems (3DTPS) can be used to design compensating filters that, in addition to missing tissue compensation, can account for tissue inhomogeneities. The use of computer-driven systems provides a practical, convenient, and accurate method of fabricating compensating filters. In this work, we have evaluated a commercially available PAR Scientific DIGIMILL milling machine linked with FOCUS 3DTPS. Compensating filters were fabricated using refined gypsum material with no additives. Thus, filters were of manageable dimensions and were not sensitive to common machining errors. Compensating filters were evaluated using a homogeneous step phantom and step phantoms containing various internal inhomogeneities (air, cork, and bone). The accuracy of two planning algorithms used to design filters was experimentally evaluated. The superposition algorithm was found to produce better agreement with measurements than the Clarkson algorithm. Phantom measurements have demonstrated that compensating filters were able to produce a uniform dose distribution along the compensation plane in the presence of tissue inhomogeneity. However, the dose variation was greatly amplified in planes located beyond the inhomogeneity when a single compensated beam was used. The use of parallel-opposed compensated beams eliminated this problem. Both lateral and depth-dose uniformity was achieved throughout the target volume.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1526-9914
pubmed:author
pubmed:copyrightInfo
(c) 2003 American College of Medical Physics.
pubmed:issnType
Electronic
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
209-16
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Effectiveness of compensating filters in the presence of tissue inhomogeneities.
pubmed:affiliation
Department of Radiation Oncology, Loyola University Medical Center, Maywood, Illinois 60153, USA. asethi@lumc.edu
pubmed:publicationType
Journal Article, Comparative Study, Evaluation Studies