|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2003-6-27
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|
pubmed:abstractText |
Periodontitis is an inflammatory disease that leads to irreversible attachment loss, bone destruction and eventually tooth loss. Tumor necrosis factor (TNF), a pluripotent proinflammatory cytokine that is able to induce tissue destruction and bone resorption, has been implicated in the pathogenesis of periodontal disease.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
D
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0022-3484
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
38
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
394-9
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|
pubmed:dateRevised |
2008-11-21
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|
pubmed:meshHeading |
pubmed-meshheading:12828656-Adenine,
pubmed-meshheading:12828656-Adult,
pubmed-meshheading:12828656-Case-Control Studies,
pubmed-meshheading:12828656-Chronic Disease,
pubmed-meshheading:12828656-Czech Republic,
pubmed-meshheading:12828656-European Continental Ancestry Group,
pubmed-meshheading:12828656-Female,
pubmed-meshheading:12828656-Gene Frequency,
pubmed-meshheading:12828656-Genetic Predisposition to Disease,
pubmed-meshheading:12828656-Genotype,
pubmed-meshheading:12828656-Guanine,
pubmed-meshheading:12828656-Humans,
pubmed-meshheading:12828656-Introns,
pubmed-meshheading:12828656-Lymphotoxin-alpha,
pubmed-meshheading:12828656-Male,
pubmed-meshheading:12828656-Middle Aged,
pubmed-meshheading:12828656-Monte Carlo Method,
pubmed-meshheading:12828656-Periodontitis,
pubmed-meshheading:12828656-Polymorphism, Genetic,
pubmed-meshheading:12828656-Promoter Regions, Genetic,
pubmed-meshheading:12828656-Tumor Necrosis Factor-alpha
|
|
pubmed:year |
2003
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|
pubmed:articleTitle |
Polymorphisms in the +252(A/G) lymphotoxin-alpha and the -308(A/G) tumor necrosis factor-alpha genes and susceptibility to chronic periodontitis in a Czech population.
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|
pubmed:affiliation |
Department of Pathological Physiology, Clinic of Stomatology, Medical Faculty and Centre for Mathematical Modelling, Masaryk University Brno, Czech Republic.
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|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
