Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2003-5-23
pubmed:abstractText
Information about alterations of hepatobiliary transporter expression in primary biliary cirrhosis (PBC) could provide important insights into the pathogenesis of cholestasis. This study aimed to determine the expression of hepatobiliary transport systems for bile salts (Na(+)/taurocholate cotransporter, NTCP; bile salt export pump, BSEP), organic anions (organic anion transporting protein, OATP2; canalicular conjugate export pump, MRP2; basolateral MRP homologue, MRP3), organic cations (canalicular multidrug export pump, MDR1), and phospholipids (canalicular phospholipid flippase MDR3) in livers from patients with advanced stages of PBC.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0168-8278
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
717-27
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:12763363-Adaptation, Physiological, pubmed-meshheading:12763363-Bile, pubmed-meshheading:12763363-Bile Acids and Salts, pubmed-meshheading:12763363-Bile Canaliculi, pubmed-meshheading:12763363-Blotting, Western, pubmed-meshheading:12763363-Carrier Proteins, pubmed-meshheading:12763363-Down-Regulation, pubmed-meshheading:12763363-Fluorescent Antibody Technique, pubmed-meshheading:12763363-Gas Chromatography-Mass Spectrometry, pubmed-meshheading:12763363-Humans, pubmed-meshheading:12763363-Immunohistochemistry, pubmed-meshheading:12763363-Liver, pubmed-meshheading:12763363-Liver Cirrhosis, Biliary, pubmed-meshheading:12763363-Microscopy, Fluorescence, pubmed-meshheading:12763363-Middle Aged, pubmed-meshheading:12763363-RNA, Messenger, pubmed-meshheading:12763363-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:12763363-Tissue Distribution, pubmed-meshheading:12763363-Up-Regulation
pubmed:year
2003
pubmed:articleTitle
Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis.
pubmed:affiliation
Division of Gastroenterology and Hepatology, Department of Medicine, Karl-Franzens University, Auenbruggerplatz 15, A-8036, Graz, Austria.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't